当前位置:首页>产品中心>单抗/多抗>Anti-Human PRPF6 Polyclonal Antibody|抗人PRPF6多克隆抗体(靶标:人前体mRNA加工因子6)

Anti-Human PRPF6 Polyclonal Antibody|抗人PRPF6多克隆抗体(靶标:人前体mRNA加工因子6)

  • 货号:RB9THD153014
  • 价格:面议
  • 点击:337

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Rat, Human, Mouse
靶标ANT-1, Androgen receptor N-terminal domain-transactivating protein 1, C20orf14, PRP6 homolog, PRPF6, Pre-mRNA-processing factor 6, U5 snRNP-associated 102 kDa protein, U5-102 kDa protein
免疫原E. coli - derived recombinant Human PRPF6 (Lys606-Phe941).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号O94906
背景信息

Pre-mRNA-processing factor 6 (PRPF6) is a ~106 kDa protein. Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation.

1. Schneider, M. et al. (2010) Nature structural & molecular biology 17, 216-21. PMID: 20118938
2. Tanackovic, G. et al. (2011) American journal of human genetics 88, 643-9. PMID: 21549338
3. Bertram, K. et al. (2017) Cell 170, 701-713.e11. PMID: 28781166
备注For research use only
【仅供科学研究使用】

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