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Anti-Human DESI2 Polyclonal Antibody|抗人DESI2多克隆抗体(靶标:人去SUMO化酶2)

  • 货号:RB9THC211014
  • 价格:面议
  • 点击:349

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Mouse, Human, Rat
靶标C1orf121, DESI2, DeSI-2, Desumoylating isopeptidase 2, Deubiquitinase DESI2, EC:3.1.2.22, EC:3.4.19.12, FAM152A, PPPDE peptidase domain-containing protein 1, PPPDE1, Palmitoyl protein thioesterase DES
免疫原E. coli - derived recombinant Human DESI2 (Met1-Leu194).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q9BSY9
背景信息

Deubiquitinase DESI2 is a ~21 kDa protein. Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization. Exhibits palmitoyl protein thioesterase (S-depalmitoylation) activity towards synthetic substrates 4-methylumbelliferyl-6-S-palmitoyl-beta-D-glucopyranoside and S-depalmitoylation probe 5 (DPP-5).

1. Xie, X. et al. (2017) Biochemical and biophysical research communications 488, 291-296. PMID: 28483520
2. Luebben, AV. et al. (2022) Science advances 8, eabj8633. PMID: 35427157
备注For research use only
【仅供科学研究使用】

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