| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Rat, Mouse |
| 靶标 | Deubiquitinating enzyme 48, EC:3.4.19.12, USP31, USP48, Ubiquitin carboxyl-terminal hydrolase 48, Ubiquitin thioesterase 48, Ubiquitin-specific peptidase 48, Ubiquitin-specific protease 48, Ubiquitin- |
| 免疫原 | E. coli - derived recombinant Human USP48 (Gln423-Val559). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q86UV5 |
| 背景信息 | Ubiquitin carboxyl-terminal hydrolase 48 (USP48) is a ~119 kDa protein. Deubiquitinase that recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of polyubiquitin precursors as well as that of ubiquitinated proteins. Plays a role in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at postsynaptic sites. Plays an important role in cell cycle progression by deubiquitinating Aurora B/AURKB and thereby extending its stability. 1. Tzimas, C. et al. (2006) Cellular signalling 18, 83-92. PMID: 16214042 2. Bassani, S. et al. (2021) Human molecular genetics 30, 1785-1796. PMID: 34059922 3. Antao, AM. et al. (2021) International journal of molecular sciences 22. PMID: 34445214 4. Jantaree, P. et al. (2022) Cellular and molecular life sciences : CMLS 79, 461. PMID: 35913642 5. Sánchez-Bellver, L. et al. (2022) International journal of molecular sciences 23. PMID: 36293380 6. Ren, Y. et al. (2023) Cancer research 83, 1074-1093. PMID: 36607699 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 阿苯达唑砜单抗 | 5537 |
| 金刚烷胺单抗 | 5598 |
| 卡那霉素单抗 | 5749 |
| 黄曲霉毒素M1(AFM1)单抗 | 5704 |
| 群勃龙(孕三烯酮)(去甲雄三烯醇酮)单抗 | 5913 |
| 帕托珠利(妥曲珠利砜)单抗 | 5613 |
| 泰乐菌素单抗 | 5662 |
| 替米考星单抗 | 5785 |
| 新霉素单抗 | 5758 |
| 安普霉素单抗 | 5710 |
| 三聚氰胺(MEL)单抗 | 5610 |
| 双氟沙星单抗 | 5565 |
| 西地那非单抗 | 5677 |
| 阿苯达唑单抗 | 5466 |
| 醋酸甲羟孕酮(醋酸甲孕酮)单抗 | 5645 |
| 氟苯尼考单抗 | 5676 |
| 诺龙单抗 | 5746 |
| 达氟沙星单抗 | 5875 |
| 培氟沙星单抗 | 5724 |
| 庆大霉素单抗 | 5873 |