| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Rat, Mouse |
| 靶标 | Deubiquitinating enzyme 48, EC:3.4.19.12, USP31, USP48, Ubiquitin carboxyl-terminal hydrolase 48, Ubiquitin thioesterase 48, Ubiquitin-specific peptidase 48, Ubiquitin-specific protease 48, Ubiquitin- |
| 免疫原 | E. coli - derived recombinant Human USP48 (Gln423-Val559). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q86UV5 |
| 背景信息 | Ubiquitin carboxyl-terminal hydrolase 48 (USP48) is a ~119 kDa protein. Deubiquitinase that recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of polyubiquitin precursors as well as that of ubiquitinated proteins. Plays a role in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at postsynaptic sites. Plays an important role in cell cycle progression by deubiquitinating Aurora B/AURKB and thereby extending its stability. 1. Tzimas, C. et al. (2006) Cellular signalling 18, 83-92. PMID: 16214042 2. Bassani, S. et al. (2021) Human molecular genetics 30, 1785-1796. PMID: 34059922 3. Antao, AM. et al. (2021) International journal of molecular sciences 22. PMID: 34445214 4. Jantaree, P. et al. (2022) Cellular and molecular life sciences : CMLS 79, 461. PMID: 35913642 5. Sánchez-Bellver, L. et al. (2022) International journal of molecular sciences 23. PMID: 36293380 6. Ren, Y. et al. (2023) Cancer research 83, 1074-1093. PMID: 36607699 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 氯丙嗪单抗 | 5787 |
| 西马特罗单抗 | 5775 |
| 孕酮单抗 | 5955 |
| 氯霉素(CAP)单抗 | 5885 |
| 红霉素单抗 | 5894 |
| 地克珠利单抗 | 5652 |
| 无色孔雀石绿(LMG)单抗 | 5873 |
| 雌二醇单抗 | 5517 |
| 孔雀石绿(MG)单抗 | 6036 |
| 双酚A单抗 | 5823 |
| 呋喃妥因代谢物(2-NPAHD)单抗 | 5676 |
| 己烯雌酚单抗 | 5706 |
| 莱克多巴胺(RAC)单抗 | 5848 |
| 林可霉素单抗 | 6144 |
| 抗青霉素受体单抗 | 5662 |
| 大观霉素单抗 | 5739 |
| 克伦特罗(CL)单抗 | 5961 |
| 沙拉沙星单抗(2H4) | 5779 |
| 磺胺对甲氧嘧啶(SMD)单抗 | 5932 |
| 磺胺类SAS单抗 | 5857 |